Pharmacological Activation of Potassium Channel Kv11.1 with NS1643 Attenuates Triple Negative Breast Cancer Cell Migration by Promoting the Dephosphorylation of Caveolin-1

The prevention of metastasis is a central goal of cancer therapy. Caveolin-1 (Cav-1) is a structural membrane and scaffolding protein shown to be a key regulator of late-stage breast cancer metastasis. However, therapeutic strategies targeting Cav-1 are still lacking. Here, we demonstrate that the p...

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Detalles Bibliográficos
Autores principales: Jiang, Ying, Senyuk, Vitalyi, Ma, Ke, Chen, Hui, Qin, Xiang, Li, Shun, Liu, Yiyao, Gentile, Saverio, Minshall, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368491/
https://www.ncbi.nlm.nih.gov/pubmed/35954304
http://dx.doi.org/10.3390/cells11152461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368491/
https://www.ncbi.nlm.nih.gov/pubmed/35954304
http://dx.doi.org/10.3390/cells11152461

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