Cargando…

The Exocyst Is Required for CD36 Fatty Acid Translocase Trafficking and Free Fatty Acid Uptake in Skeletal Muscle Cells

In obesity, chronic membrane-localization of CD36 free fatty acid (FFA) translocase, but not other FFA transporters, enhances FFA uptake and intracellular lipid accumulation. This ectopic lipid accumulation promotes insulin resistance by inhibiting insulin-induced GLUT4 glucose transporter trafficki...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakamura, Nicole K., Tokunaga, Darcy S., Ha, Herena Y., Polgar, Noemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368548/
https://www.ncbi.nlm.nih.gov/pubmed/35954283
http://dx.doi.org/10.3390/cells11152440