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Analysis of Givinostat/ITF2357 Treatment in a Rat Model of Neonatal Hypoxic-Ischemic Brain Damage

The histone deacetylase inhibitor (HDACi) Givinostat/ITF2357 provides neuroprotection in adult models of brain injury; however, its action after neonatal hypoxia-ischemia (HI) is still undefined. The aim of our study was to test the hypothesis that the mechanism of Givinostat is associated with the...

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Detalles Bibliográficos
Autores principales: Pawelec, Paulina, Sypecka, Joanna, Zalewska, Teresa, Ziemka-Nalecz, Malgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368553/
https://www.ncbi.nlm.nih.gov/pubmed/35955430
http://dx.doi.org/10.3390/ijms23158287