A Preclinical Study on Brugada Syndrome with a CACNB2 Variant Using Human Cardiomyocytes from Induced Pluripotent Stem Cells

Aims: Some gene variants in the sodium channels, as well as calcium channels, have been associated with Brugada syndrome (BrS). However, the investigation of the human cellular phenotype and the use of drugs for BrS in presence of variant in the calcium channel subunit is still lacking. Objectives:...

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Detalles Bibliográficos
Autores principales: Zhong, Rujia, Schimanski, Theresa, Zhang, Feng, Lan, Huan, Hohn, Alyssa, Xu, Qiang, Huang, Mengying, Liao, Zhenxing, Qiao, Lin, Yang, Zhen, Li, Yingrui, Zhao, Zhihan, Li, Xin, Rose, Lena, Albers, Sebastian, Maywald, Lasse, Müller, Jonas, Dinkel, Hendrik, Saguner, Ardan, Janssen, Johannes W. G., Swamy, Narasimha, Xi, Yannick, Lang, Siegfried, Kleinsorge, Mandy, Duru, Firat, Zhou, Xiaobo, Diecke, Sebastian, Cyganek, Lukas, Akin, Ibrahim, El-Battrawy, Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368582/
https://www.ncbi.nlm.nih.gov/pubmed/35955449
http://dx.doi.org/10.3390/ijms23158313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368582/
https://www.ncbi.nlm.nih.gov/pubmed/35955449
http://dx.doi.org/10.3390/ijms23158313

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