Iridium-Catalyzed Borylation of 6-Fluoroquinolines: Access to 6-Fluoroquinolones

[Image: see text] The Ir-catalyzed C–H borylation of fluoroquinolines has been realized. The quinoline boronic ester formed undergoes a range of important transformations of relevance to medicinal chemistry. Judicious choice of the substituent at C4 on the quinoline facilitated the unmasking of a fl...

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Detalles Bibliográficos
Autores principales: Hickey, Aobha, Merz, Julia, Al Mamari, Hamad H., Friedrich, Alexandra, Marder, Todd B., McGlacken, Gerard P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368603/
https://www.ncbi.nlm.nih.gov/pubmed/35839386
http://dx.doi.org/10.1021/acs.joc.2c00973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368603/
https://www.ncbi.nlm.nih.gov/pubmed/35839386
http://dx.doi.org/10.1021/acs.joc.2c00973

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