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Therapy-Induced Senescent/Polyploid Cancer Cells Undergo Atypical Divisions Associated with Altered Expression of Meiosis, Spermatogenesis and EMT Genes

Upon anticancer treatment, cancer cells can undergo cellular senescence, i.e., the temporal arrest of cell division, accompanied by polyploidization and subsequent amitotic divisions, giving rise to mitotically dividing progeny. In this study, we sought to further characterize the cells undergoing s...

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Detalles Bibliográficos
Autores principales: Czarnecka-Herok, Joanna, Sliwinska, Malgorzata Alicja, Herok, Marcin, Targonska, Alicja, Strzeszewska-Potyrala, Anna, Bojko, Agnieszka, Wolny, Artur, Mosieniak, Grazyna, Sikora, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368617/
https://www.ncbi.nlm.nih.gov/pubmed/35955416
http://dx.doi.org/10.3390/ijms23158288