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Cellular Redox Metabolism Is Modulated by the Distinct Localization of Cyclic Nucleotide Phosphodiesterase 5A Isoforms

3′-5′ cyclic nucleotide phosphodiesterases (PDEs) are a family of evolutionarily conserved cAMP and/or cGMP hydrolyzing enzymes, components of transduction pathways regulating crucial aspects of cell life. Among them, cGMP-specific PDE5—being a regulator of vascular smooth muscle contraction—is the...

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Detalles Bibliográficos
Autores principales: Cardarelli, Silvia, Miele, Adriana Erica, Campolo, Federica, Massimi, Mara, Mancini, Patrizia, Biagioni, Stefano, Naro, Fabio, Giorgi, Mauro, Saliola, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368758/
https://www.ncbi.nlm.nih.gov/pubmed/35955722
http://dx.doi.org/10.3390/ijms23158587