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Cellular Redox Metabolism Is Modulated by the Distinct Localization of Cyclic Nucleotide Phosphodiesterase 5A Isoforms
3′-5′ cyclic nucleotide phosphodiesterases (PDEs) are a family of evolutionarily conserved cAMP and/or cGMP hydrolyzing enzymes, components of transduction pathways regulating crucial aspects of cell life. Among them, cGMP-specific PDE5—being a regulator of vascular smooth muscle contraction—is the...
Autores principales: | Cardarelli, Silvia, Miele, Adriana Erica, Campolo, Federica, Massimi, Mara, Mancini, Patrizia, Biagioni, Stefano, Naro, Fabio, Giorgi, Mauro, Saliola, Michele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368758/ https://www.ncbi.nlm.nih.gov/pubmed/35955722 http://dx.doi.org/10.3390/ijms23158587 |
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