The Significance of Cell Surface N-Glycosylation for Internalization and Potency of Cytotoxic Conjugates Targeting Receptor Tyrosine Kinases

Precise anticancer therapies employing cytotoxic conjugates constitute a side-effect-limited, highly attractive alternative to commonly used cancer treatment modalities, such as conventional chemotherapy, radiotherapy or surgical interventions. Receptor tyrosine kinases are a large family of N-glyco...

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Detalles Bibliográficos
Autores principales: Poźniak, Marta, Żukowska, Dominika, Gędaj, Aleksandra, Krzyścik, Mateusz Adam, Porębska, Natalia, Zakrzewska, Małgorzata, Otlewski, Jacek, Opaliński, Łukasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368766/
https://www.ncbi.nlm.nih.gov/pubmed/35955648
http://dx.doi.org/10.3390/ijms23158514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368766/
https://www.ncbi.nlm.nih.gov/pubmed/35955648
http://dx.doi.org/10.3390/ijms23158514

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