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Computational Analysis of Short Linear Motifs in the Spike Protein of SARS-CoV-2 Variants Provides Possible Clues into the Immune Hijack and Evasion Mechanisms of Omicron Variant

Short linear motifs (SLiMs) are short linear sequences that can mediate protein–protein interaction. Mimicking eukaryotic SLiMs to compete with extra- or intracellular binding partners, or to sequester host proteins is the crucial strategy of viruses to pervert the host system. Evolved proteins in v...

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Detalles Bibliográficos
Autores principales: Soorajkumar, Anjana, Alakraf, Ebrahim, Uddin, Mohammed, Du Plessis, Stefan S., Alsheikh-Ali, Alawi, Kandasamy, Richard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368778/
https://www.ncbi.nlm.nih.gov/pubmed/35955954
http://dx.doi.org/10.3390/ijms23158822