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MicroRNA in Acromegaly: Involvement in the Pathogenesis and in the Response to First-Generation Somatostatin Receptor Ligands

Acromegaly is a chronic and systemic disease due to excessive growth hormone and insulin-like growth factor type I caused, in the vast majority of cases, by a GH-secreting pituitary adenoma. About 40% of these tumors have somatic mutations in the stimulatory G protein alpha-subunit 1 gene. The patho...

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Detalles Bibliográficos
Autores principales: Henriques, Daniel G., Lamback, Elisa B., Dezonne, Romulo S., Kasuki, Leandro, Gadelha, Monica R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368811/
https://www.ncbi.nlm.nih.gov/pubmed/35955787
http://dx.doi.org/10.3390/ijms23158653