Cargando…

Transcriptomic Analysis Reveals That Granulocyte Colony-Stimulating Factor Trigger a Novel Signaling Pathway (TAF9-P53-TRIAP1-CASP3) to Protect Retinal Ganglion Cells after Ischemic Optic Neuropathy

Optic nerve head (ONH) infarct can result in progressive retinal ganglion cell (RGC) death. The granulocyte colony-stimulating factor (GCSF) protects the RGC after ON infarct. However, protective mechanisms of the GCSF after ONH infarct are complex and remain unclear. To investigate the complex mech...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsai, Rong-Kung, Lin, Keh-Liang, Huang, Chin-Te, Wen, Yao-Tseng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368818/
https://www.ncbi.nlm.nih.gov/pubmed/35955492
http://dx.doi.org/10.3390/ijms23158359