First Experimental Evidence for Reversibility of Ammonia Loss from Asparagine

Ammonia loss from (L)-asparaginyls is a nonenzymatic reaction spontaneously occurring in all proteins and eventually resulting in damaging isoaspartate residues that hamper protein function and induce proteinopathy related to aging. Here, we discuss theoretical considerations supporting the possibil...

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Detalles Bibliográficos
Autores principales: Wang, Jijing, Rodin, Sergey, Saei, Amir Ata, Zhang, Xuepei, Zubarev, Roman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368827/
https://www.ncbi.nlm.nih.gov/pubmed/35955504
http://dx.doi.org/10.3390/ijms23158371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368827/
https://www.ncbi.nlm.nih.gov/pubmed/35955504
http://dx.doi.org/10.3390/ijms23158371

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