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Free Cholesterol Affects the Function and Localization of Human Na(+)/Taurocholate Cotransporting Polypeptide (NTCP) and Organic Cation Transporter 1 (OCT1)

Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are associated with obesity. They are accompanied by increased levels of free cholesterol in the liver. Most free cholesterol resides within the plasma membrane. We assessed the impact of adding or removing free chole...

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Detalles Bibliográficos
Autores principales: Idowu, Jessica Y., Hagenbuch, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368832/
https://www.ncbi.nlm.nih.gov/pubmed/35955590
http://dx.doi.org/10.3390/ijms23158457