Diclofenac-Induced Cytotoxicity in Direct and Indirect Co-Culture of HepG2 Cells with Differentiated THP-1 Cells

Non-steroidal anti-inflammatory drugs (NSAIDs) such as diclofenac (DIC) frequently induce drug-induced liver injury (DILI). It is unclear whether macrophages such as M1 and M2 participate in NSAID-associated DILI; elucidating this relationship could lead to a better understanding of the detailed mec...

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Detalles Bibliográficos
Autores principales: Kawase, Atsushi, Takashima, Ouka, Tanaka, Satsuki, Shimada, Hiroaki, Iwaki, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368861/
https://www.ncbi.nlm.nih.gov/pubmed/35955793
http://dx.doi.org/10.3390/ijms23158660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368861/
https://www.ncbi.nlm.nih.gov/pubmed/35955793
http://dx.doi.org/10.3390/ijms23158660

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