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Diclofenac-Induced Cytotoxicity in Direct and Indirect Co-Culture of HepG2 Cells with Differentiated THP-1 Cells
Non-steroidal anti-inflammatory drugs (NSAIDs) such as diclofenac (DIC) frequently induce drug-induced liver injury (DILI). It is unclear whether macrophages such as M1 and M2 participate in NSAID-associated DILI; elucidating this relationship could lead to a better understanding of the detailed mec...
Autores principales: | Kawase, Atsushi, Takashima, Ouka, Tanaka, Satsuki, Shimada, Hiroaki, Iwaki, Masahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368861/ https://www.ncbi.nlm.nih.gov/pubmed/35955793 http://dx.doi.org/10.3390/ijms23158660 |
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