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Downregulation of IL-8 and IL-10 by the Activation of Ca(2+)-Activated K(+) Channel K(Ca)3.1 in THP-1-Derived M(2) Macrophages

THP-1-differentiated macrophages are useful for investigating the physiological significance of tumor-associated macrophages (TAMs). In the tumor microenvironment (TME), TAMs with the M(2)-like phenotype play a critical role in promoting cancer progression and metastasis by inhibiting the immune sur...

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Detalles Bibliográficos
Autores principales: Ohya, Susumu, Matsui, Miki, Kajikuri, Junko, Kito, Hiroaki, Endo, Kyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368915/
https://www.ncbi.nlm.nih.gov/pubmed/35955737
http://dx.doi.org/10.3390/ijms23158603