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Involvement of a Cluster of Basic Amino Acids in Phosphorylation-Dependent Functional Repression of the Ceramide Transport Protein CERT

Ceramide transport protein (CERT) mediates ceramide transfer from the endoplasmic reticulum to the Golgi for sphingomyelin (SM) biosynthesis. CERT is inactivated by multiple phosphorylation at the serine-repeat motif (SRM), and mutations that impair the SRM phosphorylation are associated with a grou...

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Detalles Bibliográficos
Autores principales: Goto, Asako, Egawa, Daichi, Tomishige, Nario, Yamaji, Toshiyuki, Shimasaki, Kentaro, Kumagai, Keigo, Hanada, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368931/
https://www.ncbi.nlm.nih.gov/pubmed/35955719
http://dx.doi.org/10.3390/ijms23158576