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Involvement of a Cluster of Basic Amino Acids in Phosphorylation-Dependent Functional Repression of the Ceramide Transport Protein CERT
Ceramide transport protein (CERT) mediates ceramide transfer from the endoplasmic reticulum to the Golgi for sphingomyelin (SM) biosynthesis. CERT is inactivated by multiple phosphorylation at the serine-repeat motif (SRM), and mutations that impair the SRM phosphorylation are associated with a grou...
Autores principales: | Goto, Asako, Egawa, Daichi, Tomishige, Nario, Yamaji, Toshiyuki, Shimasaki, Kentaro, Kumagai, Keigo, Hanada, Kentaro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368931/ https://www.ncbi.nlm.nih.gov/pubmed/35955719 http://dx.doi.org/10.3390/ijms23158576 |
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