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Time-Dependent DNA Origami Denaturation by Guanidinium Chloride, Guanidinium Sulfate, and Guanidinium Thiocyanate

Guanidinium (Gdm) undergoes interactions with both hydrophilic and hydrophobic groups and, thus, is a highly potent denaturant of biomolecular structure. However, our molecular understanding of the interaction of Gdm with proteins and DNA is still rather limited. Here, we investigated the denaturati...

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Detalles Bibliográficos
Autores principales: Hanke, Marcel, Hansen, Niklas, Tomm, Emilia, Grundmeier, Guido, Keller, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368935/
https://www.ncbi.nlm.nih.gov/pubmed/35955680
http://dx.doi.org/10.3390/ijms23158547