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Hypercholesterolemia-Induced HDL Dysfunction Can Be Reversed: The Impact of Diet and Statin Treatment in a Preclinical Animal Model

High-density lipoproteins (HDL) undergo adverse remodeling and loss of function in the presence of comorbidities. We assessed the potential of lipid-lowering approaches (diet and rosuvastatin) to rescue hypercholesterolemia-induced HDL dysfunction. Hypercholesterolemia was induced in 32 pigs for 10...

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Detalles Bibliográficos
Autores principales: Schoch, Leonie, Sutelman, Pablo, Suades, Rosa, Casani, Laura, Padro, Teresa, Badimon, Lina, Vilahur, Gemma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368958/
https://www.ncbi.nlm.nih.gov/pubmed/35955730
http://dx.doi.org/10.3390/ijms23158596