A Multiscale Molecular Dynamic Analysis Reveals the Effect of Sialylation on EGFR Clustering in a CRISPR/Cas9-Derived Model

Bacterial and viral pathogens can modulate the glycosylation of key host proteins to facilitate pathogenesis by using various glycosidases, particularly sialidases. Epidermal growth factor receptor (EGFR) signaling is activated by ligand-induced receptor dimerization and oligomerization. Ligand bind...

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Detalles Bibliográficos
Autores principales: Leong, Shwee Khuan, Hsiao, Jye-Chian, Shie, Jiun-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368999/
https://www.ncbi.nlm.nih.gov/pubmed/35955894
http://dx.doi.org/10.3390/ijms23158754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368999/
https://www.ncbi.nlm.nih.gov/pubmed/35955894
http://dx.doi.org/10.3390/ijms23158754

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