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Predicting the Prognostic Value of POLI Expression in Different Cancers via a Machine Learning Approach
Translesion synthesis (TLS) is a cell signaling pathway that facilitates the tolerance of replication stress. Increased TLS activity, the particularly elevated expression of TLS polymerases, has been linked to resistance to cancer chemotherapeutics and significantly altered patient outcomes. Buildin...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369001/ https://www.ncbi.nlm.nih.gov/pubmed/35955705 http://dx.doi.org/10.3390/ijms23158571 |