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Predicting the Prognostic Value of POLI Expression in Different Cancers via a Machine Learning Approach

Translesion synthesis (TLS) is a cell signaling pathway that facilitates the tolerance of replication stress. Increased TLS activity, the particularly elevated expression of TLS polymerases, has been linked to resistance to cancer chemotherapeutics and significantly altered patient outcomes. Buildin...

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Detalles Bibliográficos
Autores principales: Xu, Xuan, Jaberi-Douraki, Majid, Wallace, Nicholas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369001/
https://www.ncbi.nlm.nih.gov/pubmed/35955705
http://dx.doi.org/10.3390/ijms23158571