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Reg-1α, a New Substrate of Calpain-2 Depending on Its Glycosylation Status

Reg-1α/lithostathine, a protein mainly associated with the digestive system, was previously shown to be overexpressed in the pre-clinical stages of Alzheimer’s disease. In vitro, the glycosylated protein was reported to form fibrils at physiological pH following the proteolytic action of trypsin. Ho...

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Detalles Bibliográficos
Autores principales: Lebart, Marie-Christine, Trousse, Françoise, Valette, Gilles, Torrent, Joan, Denus, Morgane, Mestre-Frances, Nadine, Marcilhac, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369050/
https://www.ncbi.nlm.nih.gov/pubmed/35955718
http://dx.doi.org/10.3390/ijms23158591