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Reg-1α, a New Substrate of Calpain-2 Depending on Its Glycosylation Status
Reg-1α/lithostathine, a protein mainly associated with the digestive system, was previously shown to be overexpressed in the pre-clinical stages of Alzheimer’s disease. In vitro, the glycosylated protein was reported to form fibrils at physiological pH following the proteolytic action of trypsin. Ho...
Autores principales: | Lebart, Marie-Christine, Trousse, Françoise, Valette, Gilles, Torrent, Joan, Denus, Morgane, Mestre-Frances, Nadine, Marcilhac, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369050/ https://www.ncbi.nlm.nih.gov/pubmed/35955718 http://dx.doi.org/10.3390/ijms23158591 |
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