Cargando…

Exploring Ligand Binding Domain Dynamics in the NRs Superfamily

Nuclear receptors (NRs) are transcription factors that play an important role in multiple diseases, such as cancer, inflammation, and metabolic disorders. They share a common structural organization composed of five domains, of which the ligand-binding domain (LBD) can adopt different conformations...

Descripción completa

Detalles Bibliográficos
Autores principales: D’Arrigo, Giulia, Autiero, Ida, Gianquinto, Eleonora, Siragusa, Lydia, Baroni, Massimo, Cruciani, Gabriele, Spyrakis, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369052/
https://www.ncbi.nlm.nih.gov/pubmed/35955864
http://dx.doi.org/10.3390/ijms23158732