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Exploring Ligand Binding Domain Dynamics in the NRs Superfamily
Nuclear receptors (NRs) are transcription factors that play an important role in multiple diseases, such as cancer, inflammation, and metabolic disorders. They share a common structural organization composed of five domains, of which the ligand-binding domain (LBD) can adopt different conformations...
Autores principales: | D’Arrigo, Giulia, Autiero, Ida, Gianquinto, Eleonora, Siragusa, Lydia, Baroni, Massimo, Cruciani, Gabriele, Spyrakis, Francesca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369052/ https://www.ncbi.nlm.nih.gov/pubmed/35955864 http://dx.doi.org/10.3390/ijms23158732 |
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