Development of Sesamol Carbamate-L-Phenylalanine Prodrug Targeting L-Type Amino Acid Transporter1 (LAT1) as a Potential Antiproliferative Agent against Melanoma

Sesamol is a compound reported to have anti-melanogenesis and anti-melanoma actions. Sesamol, however, has low intracellular drug concentration and fast excretion, which can limit its benefits in the clinic. To overcome this drawback and increase intracellular delivery of sesamol into the target mel...

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Detalles Bibliográficos
Autores principales: Srisongkram, Tarapong, Bahrami, Katayun, Järvinen, Juulia, Timonen, Juri, Rautio, Jarkko, Weerapreeyakul, Natthida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369069/
https://www.ncbi.nlm.nih.gov/pubmed/35955600
http://dx.doi.org/10.3390/ijms23158446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369069/
https://www.ncbi.nlm.nih.gov/pubmed/35955600
http://dx.doi.org/10.3390/ijms23158446

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