Effects of Suramin on Polycystic Kidney Disease in a Mouse Model of Polycystin-1 Deficiency

The aberrant activation of the purinergic signaling pathway has been shown to promote cyst growth and fluid secretion in autosomal dominant polycystic kidney disease (ADPKD). Suramin is an anti-parasitic drug that has strong anti-purinergic properties. Whether suramin could have a therapeutic effect...

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Detalles Bibliográficos
Autores principales: Chang, Ming-Yang, Hsu, Shen-Hsing, Ma, Li-Yi, Chou, Li-Feng, Hung, Cheng-Chieh, Tian, Ya-Chung, Yang, Chih-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369130/
https://www.ncbi.nlm.nih.gov/pubmed/35955634
http://dx.doi.org/10.3390/ijms23158499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369130/
https://www.ncbi.nlm.nih.gov/pubmed/35955634
http://dx.doi.org/10.3390/ijms23158499

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