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Metformin Preserves VE–Cadherin in Choroid Plexus and Attenuates Hydrocephalus via VEGF/VEGFR2/p-Src in an Intraventricular Hemorrhage Rat Model

Hydrocephalus induced by intraventricular hemorrhage (IVH) is associated with unfavorable prognosis. The increased permeability of choroid plexus and breakdown of the blood–brain barrier (BBB) was reported as a prominent mechanism of IVH-induced hydrocephalus, and vascular endothelial–cadherin (VE–c...

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Detalles Bibliográficos
Autores principales: Shen, Dan, Ye, Xianghua, Li, Jiawen, Hao, Xiaodi, Jin, Luhang, Jin, Yujia, Tong, Lusha, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369137/
https://www.ncbi.nlm.nih.gov/pubmed/35955686
http://dx.doi.org/10.3390/ijms23158552