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SIG-1451, a Novel, Non-Steroidal Anti-Inflammatory Compound, Attenuates Light-Induced Photoreceptor Degeneration by Affecting the Inflammatory Process

Age-related macular degeneration is a progressive retinal disease that is associated with factors such as oxidative stress and inflammation. In this study, we evaluated the protective effects of SIG-1451, a non-steroidal anti-inflammatory compound developed for treating atopic dermatitis and known t...

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Detalles Bibliográficos
Autores principales: Kikuchi, Yuki, Sugano, Eriko, Yuki, Shiori, Tabata, Kitako, Endo, Yuka, Takita, Yuya, Onoguchi, Reina, Ozaki, Taku, Fukuda, Tomokazu, Takai, Yoshihiro, Kurose, Takahiro, Tanaka, Koichi, Honma, Yoichi, Perez, Eduardo, Stock, Maxwell, Fernández, José R., Tamura, Masanori, Voronkov, Michael, Stock, Jeffry B., Tomita, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369167/
https://www.ncbi.nlm.nih.gov/pubmed/35955937
http://dx.doi.org/10.3390/ijms23158802