Cargando…
SIG-1451, a Novel, Non-Steroidal Anti-Inflammatory Compound, Attenuates Light-Induced Photoreceptor Degeneration by Affecting the Inflammatory Process
Age-related macular degeneration is a progressive retinal disease that is associated with factors such as oxidative stress and inflammation. In this study, we evaluated the protective effects of SIG-1451, a non-steroidal anti-inflammatory compound developed for treating atopic dermatitis and known t...
Autores principales: | Kikuchi, Yuki, Sugano, Eriko, Yuki, Shiori, Tabata, Kitako, Endo, Yuka, Takita, Yuya, Onoguchi, Reina, Ozaki, Taku, Fukuda, Tomokazu, Takai, Yoshihiro, Kurose, Takahiro, Tanaka, Koichi, Honma, Yoichi, Perez, Eduardo, Stock, Maxwell, Fernández, José R., Tamura, Masanori, Voronkov, Michael, Stock, Jeffry B., Tomita, Hiroshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369167/ https://www.ncbi.nlm.nih.gov/pubmed/35955937 http://dx.doi.org/10.3390/ijms23158802 |
Ejemplares similares
-
Evaluation of Local Retinal Function in Light-Damaged Rats Using Multifocal Electroretinograms and Multifocal Visual Evoked Potentials
por: Takita, Yuya, et al.
Publicado: (2023) -
Visual Responses of Photoreceptor-Degenerated Rats Expressing Two Different Types of Channelrhodopsin Genes
por: Sato, Masatoshi, et al.
Publicado: (2017) -
N-Acetylglutaminoyl-S-farnesyl-l-cysteine (SIG-1191): an anti-inflammatory molecule that increases the expression of the aquaglyceroporin, aquaporin-3, in human keratinocytes
por: Fernández, José R., et al.
Publicado: (2016) -
N-Methyl-N-Nitrosourea-Induced Photoreceptor Degeneration Is Inhibited by Nicotinamide via the Blockade of Upstream Events before the Phosphorylation of Signalling Proteins
por: Sugano, Eriko, et al.
Publicado: (2019) -
Phototoxicities Caused by Continuous Light Exposure Were Not Induced in Retinal Ganglion Cells Transduced by an Optogenetic Gene
por: Tabata, Kitako, et al.
Publicado: (2021)