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Microsatellite Instability: From the Implementation of the Detection to a Prognostic and Predictive Role in Cancers

Microsatellite instability (MSI) has been identified in several tumors arising from either germline or somatic aberration. The presence of MSI in cancer predicts the sensitivity to immune checkpoint inhibitors (ICIs), particularly PD1/PD-L1 inhibitors. To date, the predictive role of MSI is currentl...

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Detalles Bibliográficos
Autores principales: Amato, Martina, Franco, Renato, Facchini, Gaetano, Addeo, Raffaele, Ciardiello, Fortunato, Berretta, Massimiliano, Vita, Giulia, Sgambato, Alessandro, Pignata, Sandro, Caraglia, Michele, Accardo, Marina, Zito Marino, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369169/
https://www.ncbi.nlm.nih.gov/pubmed/35955855
http://dx.doi.org/10.3390/ijms23158726