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Microsatellite Instability: From the Implementation of the Detection to a Prognostic and Predictive Role in Cancers
Microsatellite instability (MSI) has been identified in several tumors arising from either germline or somatic aberration. The presence of MSI in cancer predicts the sensitivity to immune checkpoint inhibitors (ICIs), particularly PD1/PD-L1 inhibitors. To date, the predictive role of MSI is currentl...
Autores principales: | Amato, Martina, Franco, Renato, Facchini, Gaetano, Addeo, Raffaele, Ciardiello, Fortunato, Berretta, Massimiliano, Vita, Giulia, Sgambato, Alessandro, Pignata, Sandro, Caraglia, Michele, Accardo, Marina, Zito Marino, Federica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369169/ https://www.ncbi.nlm.nih.gov/pubmed/35955855 http://dx.doi.org/10.3390/ijms23158726 |
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