Technical Validation and Clinical Implications of Ultrasensitive PCR Approaches for EGFR-Thr790Met Mutation Detection in Pretreatment FFPE Samples and in Liquid Biopsies from Non-Small Cell Lung Cancer Patients

In pretreatment tumor samples of EGFR-mutated non-small cell lung cancer (NSCLC) patients, EGFR-Thr790Met mutation has been detected in a variable prevalence by different ultrasensitive assays with controversial prognostic value. Furthermore, its detection in liquid biopsy (LB) samples remains chall...

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Detalles Bibliográficos
Autores principales: Simarro, Javier, Pérez-Simó, Gema, Mancheño, Nuria, Ansotegui, Emilio, Muñoz-Núñez, Carlos Francisco, Gómez-Codina, José, Juan, Óscar, Palanca, Sarai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369170/
https://www.ncbi.nlm.nih.gov/pubmed/35955661
http://dx.doi.org/10.3390/ijms23158526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369170/
https://www.ncbi.nlm.nih.gov/pubmed/35955661
http://dx.doi.org/10.3390/ijms23158526

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