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Persistent TLR4 Activation Promotes Hepatocellular Carcinoma Growth through Positive Feedback Regulation by LIN28A/Let-7g miRNA

Chronic inflammation caused by liver damage or infection plays an important role in the development and progression of hepatocellular carcinoma (HCC). The activation of Toll-like receptors 4 (TLR4) is involved in HCC tumorigenesis. Moreover, high TLR4 expression in HCC has been linked to poor progno...

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Detalles Bibliográficos
Autores principales: Chen, I-Ting, Cheng, An-Chieh, Liu, Yi-Ting, Yan, Chieh, Cheng, Yi-Chen, Chang, Chiung-Fang, Tseng, Ping-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369227/
https://www.ncbi.nlm.nih.gov/pubmed/35955552
http://dx.doi.org/10.3390/ijms23158419