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HDAC8-Selective Inhibition by PCI-34051 Enhances the Anticancer Effects of ACY-241 in Ovarian Cancer Cells

HDAC6 is overexpressed in ovarian cancer and is known to be correlated with tumorigenesis. Accordingly, ACY-241, a selective HDAC6 inhibitor, is currently under clinical trial and has been tested in combination with various drugs. HDAC8, another member of the HDAC family, has recently gained attenti...

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Detalles Bibliográficos
Autores principales: Kim, Ji Yoon, Han, Seung Yoon, Yoo, Jung, Kim, Go Woon, Jeon, Yu Hyun, Lee, Sang Wu, Park, Jongsun, Kwon, So Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369251/
https://www.ncbi.nlm.nih.gov/pubmed/35955780
http://dx.doi.org/10.3390/ijms23158645