Lenalidomide potentially reduced the level of cell- associated HIV RNA and improved persistent inflammation in patients with HIV-associated cryptococcal meningitis a pilot study

BACKGROUND: The HIV-1 reservoir is a major barrier to curative strategies. Inflammation is an important factor for HIV-1 reservoir persistence. Lenalidomide regulates inflammatory cytokines efficiently. We examined whether lenalidomide could inhibit HIV-1 transcription and reduce systemic inflammati...

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Detalles Bibliográficos
Autores principales: Liu, Xiang, Zhu, Xueling, Peng, Xiaorong, Tao, Ran, Wan, Zhikai, Hui, Jiangjin, Guo, Yongzheng, Hang, Ying, Zhu, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369255/
https://www.ncbi.nlm.nih.gov/pubmed/35967862
http://dx.doi.org/10.3389/fcimb.2022.954814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369255/
https://www.ncbi.nlm.nih.gov/pubmed/35967862
http://dx.doi.org/10.3389/fcimb.2022.954814

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