Roles of Focal Adhesion Kinase PTK2 and Integrin αIIbβ3 Signaling in Collagen- and GPVI-Dependent Thrombus Formation under Shear

Glycoprotein (GP)VI and integrin αIIbβ3 are key signaling receptors in collagen-dependent platelet aggregation and in arterial thrombus formation under shear. The multiple downstream signaling pathways are still poorly understood. Here, we focused on disclosing the integrin-dependent roles of focal...

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Detalles Bibliográficos
Autores principales: Huang, Jingnan, Jooss, Natalie J., Fernández, Delia I., Sickmann, Albert, García, Ángel, Wichapong, Kanin, Dijkgraaf, Ingrid, Heemskerk, Johan W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369275/
https://www.ncbi.nlm.nih.gov/pubmed/35955827
http://dx.doi.org/10.3390/ijms23158688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369275/
https://www.ncbi.nlm.nih.gov/pubmed/35955827
http://dx.doi.org/10.3390/ijms23158688

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