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Paracrine IGF-1 Activates SOD2 Expression and Regulates ROS/p53 Axis in the Treatment of Cardiac Damage in D-Galactose-Induced Aging Rats after Receiving Mesenchymal Stem Cells

Aging is one of the causative agents associated with heart failure. Cell-based therapies show potential in the treatment of cardiac aging due to the characteristics of stem cells, including differentiation and the paracrine effect. This study aimed to investigate in detail the mechanism related to b...

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Detalles Bibliográficos
Autores principales: Hu, Wei-Syun, Liao, Wei-Yu, Chang, Chin-Hsien, Chen, Tung-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369306/
https://www.ncbi.nlm.nih.gov/pubmed/35956039
http://dx.doi.org/10.3390/jcm11154419