Canagliflozin Inhibits Human Endothelial Cell Inflammation through the Induction of Heme Oxygenase-1

Sodium-glucose co-transporter 2 (SGLT2) inhibitors improve cardiovascular outcomes in patients with type 2 diabetes mellitus (T2DM). Studies have also shown that canagliflozin directly acts on endothelial cells (ECs). Since heme oxygenase-1 (HO-1) is an established modulator of EC function, we inves...

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Detalles Bibliográficos
Autores principales: Peyton, Kelly J., Behnammanesh, Ghazaleh, Durante, Giovanna L., Durante, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369341/
https://www.ncbi.nlm.nih.gov/pubmed/35955910
http://dx.doi.org/10.3390/ijms23158777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369341/
https://www.ncbi.nlm.nih.gov/pubmed/35955910
http://dx.doi.org/10.3390/ijms23158777

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