Cargando…

Canagliflozin Inhibits Human Endothelial Cell Inflammation through the Induction of Heme Oxygenase-1

Sodium-glucose co-transporter 2 (SGLT2) inhibitors improve cardiovascular outcomes in patients with type 2 diabetes mellitus (T2DM). Studies have also shown that canagliflozin directly acts on endothelial cells (ECs). Since heme oxygenase-1 (HO-1) is an established modulator of EC function, we inves...

Descripción completa

Detalles Bibliográficos
Autores principales:	Peyton, Kelly J., Behnammanesh, Ghazaleh, Durante, Giovanna L., Durante, William
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369341/ https://www.ncbi.nlm.nih.gov/pubmed/35955910 http://dx.doi.org/10.3390/ijms23158777

Ejemplares similares

Canagliflozin inhibits vascular smooth muscle cell proliferation and migration: Role of heme oxygenase-1
por: Behnammanesh, Ghazaleh, et al.
Publicado: (2020)

Canagliflozin Inhibits Human Endothelial Cell Proliferation and Tube Formation
por: Behnammanesh, Ghazaleh, et al.
Publicado: (2019)

Effects of Sodium-Glucose Co-Transporter 2 Inhibitors on Vascular Cell Function and Arterial Remodeling
por: Durante, William, et al.
Publicado: (2021)

Vasoprotection by heme oxygenase-1: interactions with soluble guanylate cyclase
por: Durante, William
Publicado: (2011)

Targeting Heme Oxygenase-1 in the Arterial Response to Injury and Disease
por: Durante, William
Publicado: (2020)

SB202190 inhibits endothelial cell apoptosis via induction of autophagy and heme oxygenase-1
por: Schwartz, Margit, et al.
Publicado: (2018)

Curcumin Inhibits Acute Vascular Inflammation through the Activation of Heme Oxygenase-1
por: Xiao, Yunjun, et al.
Publicado: (2018)

Heme oxygenase-1 induction in the brain during lipopolysaccharide-induced acute inflammation
por: Maeda, Shigeru, et al.
Publicado: (2008)

Heme-heme oxygenase-2 reduces the atherosclerosis by preventing inflammation
por: Wang, Zhenzhen, et al.
Publicado: (2022)

Curcumin inhibits HCV replication by induction of heme oxygenase-1 and suppression of AKT
por: CHEN, MING-HO, et al.
Publicado: (2012)

Heme Oxygenase-1, Oxidation, Inflammation, and Atherosclerosis
por: Araujo, Jesus A., et al.
Publicado: (2012)

Lucidone suppresses dengue viral replication through the induction of heme oxygenase-1
por: Chen, Wei-Chun, et al.
Publicado: (2018)

Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction
por: Belcher, John D., et al.
Publicado: (2018)

Therapeutic potential of statins and the induction of heme oxygenase-1 in preeclampsia()
por: Ramma, Wenda, et al.
Publicado: (2014)

Protective effect of heme oxygenase induction in ethinylestradiol-induced cholestasis
por: Muchova, Lucie, et al.
Publicado: (2015)

Induction of heme oxygenase-1 with dietary quercetin reduces obesity-induced hepatic inflammation through macrophage phenotype switching
por: Kim, Chu-Sook, et al.
Publicado: (2016)

Capsaicin Ameliorates Cisplatin-Induced Renal Injury through Induction of Heme Oxygenase-1
por: Jung, Sung-Hyun, et al.
Publicado: (2014)

Heme Oxygenase, Inflammation, and Fibrosis: The Good, the Bad, and the Ugly?
por: Lundvig, Ditte M. S., et al.
Publicado: (2012)

Heme oxygenase-1 prevents murine intestinal inflammation
por: Takagi, Tomohisa, et al.
Publicado: (2018)

Heme Oxygenase Protects against Placental Vascular Inflammation and Abortion by the Alarmin Heme in Mice
por: Suttorp, Christiaan M., et al.
Publicado: (2020)

Induction of Heme Oxygenase‐1 Is Linked to the Severity of Disease in Human Abdominal Aortic Aneurysm
por: Hofmann, Anja, et al.
Publicado: (2021)

DMF inhibits PDGF-BB induced airway smooth muscle cell proliferation through induction of heme-oxygenase-1
por: Seidel, Petra, et al.
Publicado: (2010)

Induction of heme oxygenase-1 attenuates lipopolysaccharide-induced cyclooxygenase-2 expression in mouse brain endothelial cells
por: Shih, Ruey-Horng, et al.
Publicado: (2010)

Role of Heme Oxygenase in Inflammation, Insulin-Signalling, Diabetes and Obesity
por: Ndisang, Joseph Fomusi
Publicado: (2010)

Immune Regulation of Heme Oxygenase-1 in Allergic Airway Inflammation
por: Xia, Zhenwei, et al.
Publicado: (2022)

Heme Oxygenase-1 Inhibits HLA Class I Antibody-Dependent Endothelial Cell Activation
por: Zilian, Eva, et al.
Publicado: (2015)

Cysteine-independent activation/inhibition of heme oxygenase-2
por: Vukomanovic, Dragic, et al.
Publicado: (2016)

Heme oxygenase inhibition in cancers: possible tools and targets
por: Podkalicka, Paulina, et al.
Publicado: (2018)

Canagliflozin Ameliorates Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism and Inhibiting Inflammation through Induction of Autophagy
por: Xu, Zhipeng, et al.
Publicado: (2022)

Heme Oxygenase-1 Deficiency
por: Renji, Soumya, et al.
Publicado: (2021)

Heme oxygenase-1 induction attenuates imiquimod-induced psoriasiform inflammation by negative regulation of Stat3 signaling
por: Zhang, Bin, et al.
Publicado: (2016)

(E)-Guggulsterone Inhibits Dengue Virus Replication by Upregulating Antiviral Interferon Responses through the Induction of Heme Oxygenase-1 Expression
por: Chen, Wei-Chun, et al.
Publicado: (2021)

Induction of heme oxygenase-1 inhibits IL-1b nitrite oxide production in articular chondrocytes
por: Rannou, F
Publicado: (2003)

Protective effect of heme oxygenase-1 on Wistar rats with heart failure through the inhibition of inflammation and amelioration of intestinal microcirculation
por: Zhang, Li, et al.
Publicado: (2015)

Induction of heme oxygenase-1 protects against nutritional fibrosing steatohepatitis in mice
por: Wang, Rong Qi, et al.
Publicado: (2011)

Heme oxygenase induction attenuates TNF-α-induced hypertension in pregnant rodents
por: George, Eric M., et al.
Publicado: (2015)

Hemin inhibits NO production by IL-1β-stimulated human astrocytes through induction of heme oxygenase-1 and reduction of p38 MAPK activation
por: Sheng, Wen S, et al.
Publicado: (2010)

Heme Oxygenase-1 as a Modulator of Intestinal Inflammation Development and Progression
por: Sebastián, Valentina P., et al.
Publicado: (2018)

The Nuclear Translocation of Heme Oxygenase-1 in Human Diseases
por: Yang, Qing, et al.
Publicado: (2022)

Diabetes-Related Induction of the Heme Oxygenase System and Enhanced Colocalization of Heme Oxygenase 1 and 2 with Neuronal Nitric Oxide Synthase in Myenteric Neurons of Different Intestinal Segments
por: Chandrakumar, Lalitha, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_nkblj54s04o9o7ph39p3dmutch