Naegleria fowleri Cathepsin B Induces a Pro-Inflammatory Immune Response in BV-2 Microglial Cells via NF-κB and AP-1 Dependent-MAPK Signaling Pathway

Naegleria fowleri is a ubiquitous protozoa parasite that can cause primary amoebic meningoencephalitis (PAM), a fatal brain infection in humans. Cathepsin Bs of N. fowleri (NfCBs) are multifamily enzymes. Although their pathogenic mechanism in PAM is not clearly understood yet, NfCBs have been propo...

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Detalles Bibliográficos
Autores principales: Lê, Hương Giang, Kang, Jung-Mi, Võ, Tuấn Cường, Na, Byoung-Kuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369353/
https://www.ncbi.nlm.nih.gov/pubmed/35955520
http://dx.doi.org/10.3390/ijms23158388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369353/
https://www.ncbi.nlm.nih.gov/pubmed/35955520
http://dx.doi.org/10.3390/ijms23158388

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