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Sulforaphane Increase Mitochondrial Biogenesis-Related Gene Expression in the Hippocampus and Suppresses Age-Related Cognitive Decline in Mice

Sulforaphane (SFN) is a potent activator of the transcriptional factor, Nuclear Factor Erythroid 2 (NF-E2)-Related factor 2 (NRF2). SFN and its precursor, glucoraphanin (sulforaphane glucosinolate, SGS), have been shown to ameliorate cognitive function in clinical trials and in vivo studies. However...

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Detalles Bibliográficos
Autores principales: Shimizu, Sunao, Kasai, Shuya, Yamazaki, Hiromi, Tatara, Yota, Mimura, Junsei, Engler, Máté János, Tanji, Kunikazu, Nikaido, Yoshikazu, Inoue, Takuro, Suganuma, Hiroyuki, Wakabayashi, Koichi, Itoh, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369397/
https://www.ncbi.nlm.nih.gov/pubmed/35955572
http://dx.doi.org/10.3390/ijms23158433