Cargando…
Sulforaphane Increase Mitochondrial Biogenesis-Related Gene Expression in the Hippocampus and Suppresses Age-Related Cognitive Decline in Mice
Sulforaphane (SFN) is a potent activator of the transcriptional factor, Nuclear Factor Erythroid 2 (NF-E2)-Related factor 2 (NRF2). SFN and its precursor, glucoraphanin (sulforaphane glucosinolate, SGS), have been shown to ameliorate cognitive function in clinical trials and in vivo studies. However...
Autores principales: | Shimizu, Sunao, Kasai, Shuya, Yamazaki, Hiromi, Tatara, Yota, Mimura, Junsei, Engler, Máté János, Tanji, Kunikazu, Nikaido, Yoshikazu, Inoue, Takuro, Suganuma, Hiroyuki, Wakabayashi, Koichi, Itoh, Ken |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369397/ https://www.ncbi.nlm.nih.gov/pubmed/35955572 http://dx.doi.org/10.3390/ijms23158433 |
Ejemplares similares
-
Regulation of Nrf2 by Mitochondrial Reactive Oxygen Species in Physiology and Pathology
por: Kasai, Shuya, et al.
Publicado: (2020) -
Role of the ISR-ATF4 pathway and its cross talk with Nrf2 in mitochondrial quality control
por: Kasai, Shuya, et al.
Publicado: (2019) -
Inducible Systemic Gcn1 Deletion in Mice Leads to Transient Body Weight Loss upon Tamoxifen Treatment Associated with Decrease of Fat and Liver Glycogen Storage
por: Liu, Jun, et al.
Publicado: (2022) -
JDP2 is directly regulated by ATF4 and modulates TRAIL sensitivity by suppressing the ATF4–DR5 axis
por: Engler, Máté János, et al.
Publicado: (2020) -
Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice
por: Yamazaki, Hiromi, et al.
Publicado: (2020)