Luteolin Treatment Ameliorates Brain Development and Behavioral Performance in a Mouse Model of CDKL5 Deficiency Disorder

CDKL5 deficiency disorder (CDD), a rare and severe neurodevelopmental disease caused by mutations in the X-linked CDKL5 gene, is characterized by early-onset epilepsy, intellectual disability, and autistic features. Although pharmacotherapy has shown promise in the CDD mouse model, safe and effectiv...

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Detalles Bibliográficos
Autores principales: Tassinari, Marianna, Mottolese, Nicola, Galvani, Giuseppe, Ferrara, Domenico, Gennaccaro, Laura, Loi, Manuela, Medici, Giorgio, Candini, Giulia, Rimondini, Roberto, Ciani, Elisabetta, Trazzi, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369425/
https://www.ncbi.nlm.nih.gov/pubmed/35955854
http://dx.doi.org/10.3390/ijms23158719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369425/
https://www.ncbi.nlm.nih.gov/pubmed/35955854
http://dx.doi.org/10.3390/ijms23158719

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