Low Doses of Celecoxib Might Promote Phenotype Switching in Cutaneous Melanoma Treated with Dabrafenib—Preliminary Study

Background: Cutaneous melanoma is a heterogeneous tumor with a rapidly switching molecular and cellular phenotype. The invasive phenotype switching characterized by MITF(low)/AXL(high) predicts early resistance to multiple targeted drugs in melanoma. Celecoxib proved to be a valuable adjuvant in cut...

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Detalles Bibliográficos
Autores principales: Tudor, Diana Valentina, Florea, Adrian, Cenariu, Mihai, Olteanu, Diana Elena, Farcaș, Marius, Hopârtean, Andreea, Clichici, Simona Valeria, Filip, Gabriela Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369555/
https://www.ncbi.nlm.nih.gov/pubmed/35956175
http://dx.doi.org/10.3390/jcm11154560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369555/
https://www.ncbi.nlm.nih.gov/pubmed/35956175
http://dx.doi.org/10.3390/jcm11154560

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