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Low Doses of Celecoxib Might Promote Phenotype Switching in Cutaneous Melanoma Treated with Dabrafenib—Preliminary Study
Background: Cutaneous melanoma is a heterogeneous tumor with a rapidly switching molecular and cellular phenotype. The invasive phenotype switching characterized by MITF(low)/AXL(high) predicts early resistance to multiple targeted drugs in melanoma. Celecoxib proved to be a valuable adjuvant in cut...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369555/ https://www.ncbi.nlm.nih.gov/pubmed/35956175 http://dx.doi.org/10.3390/jcm11154560 |