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Cell Death Triggers Induce MLKL Cleavage in Multiple Myeloma Cells, Which may Promote Cell Death

Necroptosis is a type of caspase-independent programmed cell death that has been implicated in cancer development. Activation of the canonical necroptotic pathway is often characterized with successive signaling events as the phosphorylation of mixed lineage kinase domain-like (MLKL) by receptor-int...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Wang, Shiyu, Blokhuis, Bart, Ruijtenbeek, Rob, Garssen, Johan, Redegeld, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369655/
https://www.ncbi.nlm.nih.gov/pubmed/35965541
http://dx.doi.org/10.3389/fonc.2022.907036