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The Small Molecule PPARγ Agonist GL516 Induces Feeding-Stimulatory Effects in Hypothalamus Cells Hypo-E22 and Isolated Hypothalami

PPARγ agonists are implicated in the regulation of diabetes and metabolic syndrome and have therapeutic potential in brain disorders. PPARγ modulates appetite through its central effects, especially on the hypothalamic arcuate nucleus (ARC). Previous studies demonstrated that the small molecule GL51...

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Detalles Bibliográficos
Autores principales: Chiavaroli, Annalisa, di Giacomo, Viviana, De Filippis, Barbara, Cataldi, Amelia, Ferrante, Claudio, Giampietro, Letizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369729/
https://www.ncbi.nlm.nih.gov/pubmed/35956831
http://dx.doi.org/10.3390/molecules27154882